Research Studies

Research Studies

The Center On Aging is recruiting subjects for the following research studies:

PRISM 2.0 (CREATE; S. Czaja PI)

This project (funded by NIH) is an extension of PRISM (Personalized Reminder Information and Social Management System) and will evaluate an expanded version of PRISM (PRISM 2) with diverse populations of older adults in diverse contexts. PRISM 2.0 will have expanded functionality; new platforms (tablet); will be available in English and Spanish; and evaluated in rural locations, assisted living facilities, and senior housing units. We will enroll 250 ethnically diverse older adults in the trial, who will each receive a tablet. This project will yield rigorous evidence about the value of PRISM 2 for a broad array of seniors with different needs and circumstances and will examine the impact of access to PRISM 2 on social connectivity, engagement, social support, and loneliness. To find out more about the study click here or call us at 305-355-9200

Care Partners Program (S. Czaja & D. Loewenstein PIs)

This innovative study (funded by NIH) will develop and test the efficacy of an intervention, delivered through state-of-the art computer technology (laptop) for family caregivers and patients with Alzheimer’s disease (AD). A novel feature of the investigation is its focus on both the family caregiver and the patient with AD and the integration of an augmented evidenced-based caregiver intervention and evidenced-based cognitive/functional training for the patient. Two hundred and forty Hispanic, African American and White/Caucasian dyads will be enrolled in the project. To find out more about the study click here or call us at 305-355-9200 .

ACT Study (S. Czaja, PI)

The purpose of this research study is to examine a mild form of brain stimulation called Transcranial Direct Current Stimulation (tDCS) and its effect on thinking and memory improvement with brain training in older adults. This multisite randomized clinical trial will examine the individual and combined impact of pairing cognitive training with tDCS in older adults experiencing age-related cognitive changes. We are expected to enroll 120 older adults. To find out more about the study click here or call us at 305-355-9200 .

DETECT pAD (D. Loewenstein, PI)

This study examines the efficacy of newly developed and novel cognitive tests in detecting subtle cognitive and functional impairments and the progression of these impairments over time. It will help identify better ways to detect and treat early cognitive impairment. We are enrolling English and Spanish participants 60+ with normal memory, those with mild memory complaints or other cognitive concerns as long as they have not been diagnosed with dementia. To find out more about the study click here or call us at 305-355-9037.

CREATE III

Computer-Based Tasks

Project Care

Lithium Study (E. Crocco, University of Miami PI)

This NIA Phase 2, Treatment of Psychosis and Agitation in Alzheimer’s Disease funded through Columbia University Medical Center and the University. To compare changes in agitation/aggression with or without psychosis in individuals with AD who receive 12 weeks of randomized treatment with lithium or placebo. We will identify, recruit, assess, and follow to study completion of 10 subjects ages 55-95 years and their caregivers for each year (Phases II-IV) of the project for a total of 30 subjects and 30 caregivers. To find out more about the study call us at 305-355-9065.

TRIAD Study (E. Crocco, PI)

The TRIAD Research Study is currently evaluating an investigational medication (AVP-786) versus placebo to see if it may reduce symptoms of agitation due to Alzheimer’s disease. There are currently no FDA-approved medications to treat agitation in Alzheimer’s disease. Curbing the agitation and disruptive behavior could be an important step in allowing patients to return to behaving more like themselves. Therefore, caregivers may feel less distressed and be more able to provide adequate care. We will enroll 10 adults between 50 and 90 years of age with moderate to severe agitation due to Alzheimer’s disease and their caregivers. To find out more about the study call us at 305-355-9065.

iDEAS Study (E. Crocco, PI)

Funded by the American College of Radiology (ACR), 2-3 year study, exploring how brain imaging helps guide doctors in how to treat individuals with MCI, and whether these changes in treatment lead to better medical outcomes. To find out more about the study call us at 305-355-9065.

If you are interested in participating please call: 305-355-9200